Best Chaos Inoculation builds in Path of Exile 2

Path of Exile 2 has been in early access for a few months now, and players are continuously exploring new builds for their characters. One of the ones gaining steam is Chaos Inoculation build—although it’s tricky to get it right.

There are a few reasons why Chaos Inoculation build is vastly different from others in PoE 2. Most importantly, it reduces your health to one, making you rely defensively on Energy Shield. It’s a high-risk, high-reward option that’s simultaneously fun and satisfying.

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